18-08-2021, 10:29 PM
August 2021
| 14th | Premier League | Man Utd | 5 – 1 | Leeds | W |
| 22nd | Premier League | Southampton | 1 – 1 | Man Utd | D |
| 29th | Premier League | Wolves | 0 – 1 | Man Utd | W |
18-08-2021, 10:29 PM
18-08-2021, 10:36 PM
September 2021
| 11th | Premier League | Man Utd | 4 – 1 | Newcastle | W |
| 14th | Champions League | Young Boys | 2 – 1 | Man Utd | L |
| 19th | Premier League | West Ham | 1 – 2 | Man Utd | W |
| 22nd | EFL Cup | Man Utd | 0 – 1 | West Ham | L |
| 25th | Premier League | Man Utd | 0 – 1 | Aston Villa | L |
| 29th | Champions League | Man Utd | 2 – 1 | Villarreal | W |
18-08-2021, 10:40 PM
October 2021
| 2nd | Premier League | Man Utd | 1 – 1 | Everton | D |
| 16th | Premier League | Leicester | 4 – 2 | Man Utd | L |
| 20th | Champions League | Man Utd | 3 – 2 | Atalanta | W |
| 24th | Premier League | Man Utd | 0 – 5 | Liverpool | L |
| 30th | Premier League | Tottenham | 0 – 3 | Man Utd | W |
27-09-2021, 05:52 PM
November 2021
| 2nd | Champions League | Atalanta | 2 – 2 | Man Utd | D |
| 6th | Premier League | Man Utd | 0 – 2 | Man City | L |
| 20th | Premier League | Watford | 4 – 1 | Man Utd | L |
| 23rd | Champions League | Villarreal | 0 – 2 | Man Utd | W |
| 28th | Premier League | Chelsea | 1 – 1 | Man Utd | D |
28-11-2021, 06:39 PM
December 2021
| 2nd | Premier League | Man Utd | 3 – 2 | Arsenal | W |
| 5th | Premier League | Man Utd | 1 – 0 | C. Palace | W |
| 8th | Champions League | Man Utd | 1 – 1 | Young Boys | D |
| 11th | Premier League | Norwich | 0 – 1 | Man Utd | W |
| 27th | Premier League | Newcastle | 1 – 1 | Man Utd | D |
| 30th | Premier League | Man Utd | 3 – 1 | Burnley | W |
29-12-2021, 06:49 AM
January 2022
| 3rd | Premier League | Man Utd | 0 – 1 | Wolves | L |
| 10th | FA Cup | Man Utd | 1 – 0 | Aston Villa | W |
| 15th | Premier League | Aston Villa | 2 – 2 | Man Utd | D |
| 19th | Premier League | Brentford | 1 – 3 | Man Utd | W |
| 22nd | Premier League | Man Utd | 1 – 0 | West Ham | W |
21-01-2022, 09:13 AM
February 2022
| 4th | FA Cup | Man Utd | 1 – 2 | Middlesbrough | L |
| 8th | Premier League | Burnley | 1 – 1 | Man Utd | D |
| 12th | Premier League | Man Utd | 1 – 1 | Southampton | D |
| 15th | Premier League | Man Utd | 2 – 0 | Brighton | W |
| 20th | Premier League | Leeds | 2 – 4 | Man Utd | W |
| 23rd | Champions League | Atletico | 1 – 1 | Man Utd | D |
| 26th | Premier League | Man Utd | 0 – 0 | Watford | D |
26-02-2022, 05:33 PM
March 2022
| 6th | Premier League | Man City | 4 – 1 | Man Utd | L |
| 12th | Premier League | Man Utd | 3 – 2 | Tottenham | W |
| 15th | Champions League | Man Utd | 0 – 1 | Atletico | L |
19-03-2022, 12:27 AM
April 2022
| 2nd | Premier League | Man Utd | 1 – 1 | Leicester | D |
| 9th | Premier League | Everton | 1 – 0 | Man Utd | L |
| 16th | Premier League | Man Utd | 3 – 2 | Norwich | W |
| 19th | Premier League | Liverpool | 4 – 0 | Man Utd | L |
| 23rd | Premier League | Arsenal | 3 – 1 | Man Utd | L |
| 28th | Premier League | Man Utd | 1 – 1 | Chelsea | D |
29-04-2022, 12:20 PM
May 2022
| 2nd | Premier League | Man Utd | 3 – 0 | Brentford | W |
| 7th | Premier League | Brighton | 4 – 0 | Man Utd | L |
| 22nd | Premier League | C. Palace | 1 – 0 | Man Utd | L |